Quick prediction: Liverpool vs Atletico Madrid
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Anfield has hosted more than its share of memorable European nights, and Wednesday’s UEFA Champions League league-phase opener between Liverpool and Atletico Madrid on September 9, 2026 slots straight into the tradition, Afrik-Foot reports.
Super Eagles winger Ademola Lookman is set to feature for the visitors on Merseyside as the two clubs meet for the ninth time, on an evening that carries added significance for both dressing rooms.
For the hosts, this is the first Champions League fixture of the Andoni Iraola era at Anfield following Arne Slot’s May 2026 departure, and one that arrives on the back of a mixed opening three Premier League matches.
For Atletico, it is Diego Simeone’s 15th consecutive Champions League campaign in charge of Los Colchoneros.
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Liverpool vs Atletico Madrid match preview
Iraola arrives in the Champions League with a Liverpool project still in early construction.
Mohamed Salah’s departure after nine seasons at Anfield has been the summer’s most consequential storyline, and the club’s response has been to bring in Bradley Barcola from Paris Saint-Germain in a deal worth up to £123 million, alongside a loan capture of Ronald Araujo from Barcelona and the arrival of French defender Jeremy Jacquet.
The early Premier League returns have been solid rather than spectacular. Liverpool drew 2-2 at home with Newcastle United, drew 2-2 with Nottingham Forest, then beat Ipswich Town 2-0 at Portman Road last Friday for their first league win of the campaign.
Alexander Isak scored twice inside nine minutes in that victory and now has three goals in three appearances, forming a working partnership with Florian Wirtz. Liverpool sit sixth in the Premier League with five points from a possible nine.
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Atletico Madrid arrive in England in an uncomfortable place. Simeone’s side opened their La Liga season with a 2-0 win at Malaga, drew 2-2 with Villarreal, defeated Sevilla 3-1 at the Ramón Sánchez Pizjuán, and then collapsed to a chastening 3-0 defeat at Athletic Club at San Mamés on Saturday.
That result raised legitimate defensive questions four days before a trip to Anfield, and it directly involved Lookman, who was substituted in the 58th minute of a game he never got into.
Atletico sit sixth in LaLiga with seven points from four matches, five points adrift of Barcelona at the summit.
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Head-to-head record: Liverpool vs Atletico Madrid
The two clubs have crossed paths six times in the Champions League since 2020, and Liverpool hold the overall edge with three wins to Atletico’s two.
The most recent meeting came in the 2025/26 league phase at Anfield, when Liverpool prevailed 3-2 in a game that produced attacking football, confirming the pattern of high-scoring Anfield fixtures between the clubs.
The 2021/22 group stage produced two tight games, with Liverpool winning 3-2 at the Estadio Metropolitano in October and 2-0 at Anfield in November.
Atletico’s most significant success in the fixture remains the 2019/20 round of 16, when they won 1-0 in Madrid before pulling off a stunning 3-2 extra-time victory at Anfield to progress 4-2 on aggregate.
That evening remains one of the most iconic Simeone European nights of his tenure.
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Team news: Liverpool vs Atletico Madrid
Liverpool
Iraola faces a defensive shortage that has forced some improvisation. Conor Bradley, Joe Gomez and Giovanni Leoni are all sidelined, thinning the full-back options.
Federico Chiesa and Wataru Endo were left out of the Champions League squad entirely, and Hugo Ekitike also remains out after undergoing surgery on his Achilles.
The bright spot has been Barcola. The £106 million French winger produced a promising 26-minute cameo at Ipswich, clocking the fastest recorded speed of any Premier League player this season at 35.9 km/h, and is in contention for his first competitive Anfield start.
Isak’s opening-day understanding with Wirtz and Cody Gakpo has been the other clear positive.
| Liverpool predicted XI (4-2-3-1) | ||
|---|---|---|
| Position | Player | Nation |
| GK | Alisson Becker | 🇧🇷 |
| RB | Ronald Araujo | 🇺🇾 |
| CB | Virgil van Dijk | 🇳🇱 |
| CB | Jeremy Jacquet | 🇫🇷 |
| LB | Milos Kerkez | 🇭🇺 |
| CM | Ryan Gravenberch | 🇳🇱 |
| CM | Dominik Szoboszlai | 🇭🇺 |
| RW | Cody Gakpo | 🇳🇱 |
| AM | Florian Wirtz | 🇩🇪 |
| LW | Bradley Barcola | 🇫🇷 |
| ST | Alexander Isak | 🇸🇪 |
Ademola Lookman and the Atletico injury picture
Atletico’s situation is murkier. Alexander Sorloth remains sidelined through injury; Arnau Ortiz is serving an ongoing suspension dating back to August 2024.
Julian Alvarez is back in the squad after briefly missing a few games amid summer interest from Barcelona but has been eased back into action after coming off the bench in the Athletic Club defeat.
For Lookman, the Anfield trip is a chance to respond to a difficult Saturday. Former Arsenal and West Ham midfielder Stewart Robson criticised the Super Eagles winger‘s “isolation on the left flank” at San Mamés, and Simeone will hope that a bigger occasion produces a bigger response.
| Atletico Madrid predicted XI (4-4-2) | ||
|---|---|---|
| Position | Player | Nation |
| GK | Jan Oblak | 🇸🇮 |
| RB | Marcos Llorente | 🇪🇸 |
| CB | Marc Pubill | 🇪🇸 |
| CB | David Hancko | 🇸🇰 |
| LB | Alejandro Grimaldo | 🇪🇸 |
| RM | Giuliano Simeone | 🇦🇷 |
| CM | Morten Hjulmand | 🇩🇰 |
| CM | Pablo Barrios | 🇪🇸 |
| LM | Ademola Lookman | 🇳🇬 |
| ST | Alex Baena | 🇪🇸 |
| ST | Julian Alvarez | 🇦🇷 |
Star player comparison: Alexander Isak vs Alex Baena
| Metric | Alexander Isak (Liverpool) | Alex Baena (Atletico Madrid) |
|---|---|---|
| Position | Striker | Attacking midfielder |
| 2026/27 league goals | 3 | 3 |
| 2026/27 league assists | 0 | 1 |
| League appearances | 3 | 4 |
| FotMob average rating | 7.60 | 7.54 |
The managers: Andoni Iraola vs Diego Simeone
Andoni Iraola is Liverpool’s plan for the future. The Basque tactician built his reputation at Rayo Vallecano before turning a limited Bournemouth squad into one of the most pleasing sides to watch in the Premier League across three seasons on the south coast.
Wednesday is his Champions League debut as Liverpool head coach and his first opportunity to introduce himself on the European stage against a manager whose CV in the competition is no easy feat.
“When you start your coaching career, this is one of the dreams,” Iraola said to All Football about his Champions League debut at Anfield.
“When I began, I dreamed of being in this position one day, so I hope I can savour this moment.”
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Diego Simeone’s record of more than 59% wins across 804 matches, two LaLiga titles, and two Champions League finals cements his status as one of the high-achieving managers in modern football, but the trophy that has eluded him for 15 years remains the one Liverpool won as recently as 2019.
Simeone’s Atletico have historically been at their most dangerous in games where they are billed as the underdog.
Tactical preview – Iraola’s press against Simeone’s block
Iraola is likely to deploy his usual 4-2-3-1 built around a high press and rapid recovery of possession in the opposition’s half.
The plan will be to pressure Jan Oblak and Atletico’s centre-backs into rushed distribution, create transition opportunities into Isak’s runs, and use Barcola and Gakpo’s width to stretch Simeone’s compact block.
Ryan Gravenberch and Dominik Szoboszlai carry the double burden of filter and launching pad, while Wirtz will operate in the pockets between the lines to feed Isak.
The vulnerability sits in the centre-back pairing. Jacquet and Van Dijk together represent an inexperienced partnership at Champions League level, and the Dutchman will have to compensate for the loss of the more-experienced players he’s used to playing alongside.
Ronald Araujo’s loan arrival helps at the margins, but the Uruguayan is still finding his feet in an Iraola system.
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Simeone will lean on a compact 4-4-2 with narrow lines, looking to trap Liverpool on the counter and exploit rapid transitions through Baena and Giuliano Simeone.
Alejandro Grimaldo at left-back offers an unusual attacking outlet for a Simeone full-back and is a specific matchup Iraola will need to prepare for.
Ademola Lookman is likely to be deployed wide on the left in the 4-4-2. Whether Simeone tweaks that role or trusts the Nigerian to find his own rhythm at Anfield may define Atletico’s attacking output.
The wider concern for the Spanish side is defensive cohesion. The Hancko and Pubill centre-back partnership has not yet demonstrated European-level solidity, and San Mames showed the block can fracture under sustained pressure.
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